Uses
MLCK inhibitor peptide 18 is a myosin light chain kinase (MLCK) inhibitor with an IC50 of 50 nM, and inhibits CaM kinase II only at 4000-fold higher concentrations.
Biological Activity
Cell permeable: yes', 'Primary Target
Mlck', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 50 nM against MLCK
References
[1] Lukas TJ, et al. Identification of novel classes of protein kinase inhibitors using combinatorial peptide chemistry based on functional genomics knowledge. J Med Chem. 1999 Mar 11;42(5):910-9.
