Uses
Man transferase substrate
Uses
Guanosine 5′-diphospho-D-mannose sodium salt has been used as a component of ATP regeneration system for
in vitro vesicle formation from
Saccharomyces cerevisiae microsomes. It has also been used as a component of the buffer for mannosyl transferase activity assay.
General Description
Guanosine 5′-diphospho-D-mannose (GDP-D-mannose) is present in high cytosolic levels in
Saccharomyces cerevisiae. It is crucial for protein mannosylation. GDP-D-mannose is an important precursor to produce GDP-l-fucose.
Biochem/physiol Actions
Guanosine diphosphate mannose (GDP-mannose) is a nucleotide sugar substrate for glycosyltransferase (mannosylation) reactions mediated by mannosyltransferases.
