Uses
Isoetharine Mesylate Salt is a β-adrenergic receptor agonist. Also, it is pregnane X receptor (PXR) activator capable of upregulating CYP450 expression.
brand name
Bronk ometer (Sanofi Aventis).
Biological Activity
Isoetharine is an agonist for β-adrenergic receptors and is a bronchodilator. It is a catecholic drug metabolized by sulfotransferases and is present in human urine and plasma as a sulfated metabolite. Catechol O-methyltransferase (COMT) also mediates the methylation of isoetharine in the metabolic conjugation pathway.