Description
Trestolone, also known as 7α-methyl-19-nortestosterone (MENT), is an experimental androgen/anabolic steroid (AAS) and progestogen medication which has been under development for potential use as a form of hormonal birth control for men and in androgen replacement therapy for low testosterone levels in men but has never been marketed for medical use.
Uses
Trestolone is a synthetic androgen used as a potential hormonal male contraceptive method that induces a state of termporary infertility.
Mechanism of action
Trestolone
is a potent inhibitor of the release of the luteinizing hormone (LH)
and follicle stimulating hormone (FSH). As spermatogenesis requires both
testosterone and FSH, it is impaired by the reduction in FSH caused by
trestolone as well as the reduction in LH, and subsequent reduction in
testosterone.
Side effects
Side effects of trestolone include low estrogen levels and associated symptoms such as reduced sexual function and decreased bone mineral density among others.
