Chemical Properties
Beige to yellow crystalline powder
Uses
2-Hydroxy-5-nitrobenzyl bromide was used in covalent modification of tryptophan and tryptophan residues in monoclonal immunoglobulin. It was also used as reagent for sulfhydryl modification
Uses
Reagent for sulfhydryl modification.1
Uses
2-Hydroxy-5-nitrobenzyl bromide is a chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules..
Synthesis Reference(s)
Journal of the American Chemical Society, 86, p. 1448, 1964
DOI: 10.1021/ja01061a045
General Description
2-Hydroxy-5-nitrobenzyl bromide is a protein modifying reagent.
Purification Methods
Crystallise the bromide from *benzene or *benzene/ligroin. It is slightly soluble in EtOH, soluble in *C6H6 and AcOH, and very soluble in ligroin. [Beilstein 6 H 367.]
