Reaction
- Asymmetric hetero Diels-Alder reaction catalyzed by chiral lanthanide(III) complex.
- Highly efficient Mannich reaction
- Acidic Resolving agent for certain amine/racemic mixtures.
Chemical Properties
white to light yellow crystal powde
Uses
Used as a chiral Bronsted acid catalyst in the enantoselective Mannich reaction.
Uses
The S enantiomer of binaphthol derivative as chiral quenching agent.
Purification Methods
Recrystallise it from EtOH. Reflux for 3hours in N NaOH is required to hydrolyse the cyclic phosphate. [Jacques et al. Tetrahedron Lett 4617 1971, Arnold et al. Tetrahedron 24, 343 1983.]