Allergy symptoms
Glyceryl mono thioglycolate has been recognized as a potential sensitizer and has been reported to cause allergic contact dermatitis in both hairdressers and clients. Hairdressers most commonly manifest their allergy as a hand dermatitis, whereas the clients most often have a dermatitis involving the scalp, face, ears, and neck. In preliminary patch testing, hair recently permanently woven with a solution containing glyceryl monothioglycolate produced positive results. These observations suggested that the permanent-waved hair may retain glyceryl monothioglycolate or a cross-reacting product. Positive reactions were seen in hair collected as long as 3 months after the permanent. This suggests that a glyceryl monothioglycolate-related allergen is retained in hair for up to 3 months after the permanent, which may explain the long-lasting dermatitis in clients sensitive to glyceryl monothioglycolate[1].
Description
Glyceryl monothioglycolate is an acid permanent wave
ingredient, which induces contact dermatitis in hairdressers.
Uses
Glyceryl monothio-glycolate is a component in "acid" permanent waving formulations, mainly for use in hairdressing salons.
Definition
ChEBI: Glyceryl monothioglycolate is a thioglycolate ester resulting from esterification of thioglycolic acid with glycerol. As a component of developer solutions in permanent wave products, it is the second most frequent allergen in hairdressers and avoidance of acid permanent waves is mandatory. It has a role as an allergen.
Hazard
A mild skin and eye irritant
Flammability and Explosibility
Non flammable
Contact allergens
It is an acid permanent-wave ingredient, which induces
contact dermatitis in hairdressers.
References
[1] Lynne H. Morrison M.D. , Frances J. Storrs M.D. “Persistence of an allergen in hair after glyceryl monothioglycolate—containing permanent wave solutions.” Journal of the American Academy of Dermatology 19 1 (1988): Pages 52-59.
