1-METHYL-3-INDOLEACETIC ACID

Chemical Properties

Light Brown Solid

Uses

• Reactant for enantioselective preparation of α-aryl alkylcarboxylic acids
• Reactant for preparation of PKC inhibitor methylindolylpyridinylmethylpiperidinylindolylpyrroledione for protein kinase C imaging
• Reactant for stereoselective preparation of δ-lactones via Michael addition/lactonization with unsaturated carboxylates
• Reactant for stereoselective preparation of vindorosine, vindoline, and analogs
• Reactant for preparation of (indolyl)pyrrol-2-ones as VEGF-R inhibitors, antiangiogenic agents, and protein kinase inhibitors
• Reactant for synthesis of 3-aryl-5-alkyl-2,5-dihydrofuran-2-ones and their carbanalogues as antifungal agents

Uses

1-Methylindole-3-acetic Acid is a N-methylated derivative of Indole-3-acetic acid, a natural auxin, with plant growth regulating activity.

General Description

1-Methyl-3-indoleacetic acid is an indole derivative. Direct and riboflavin- or Rose-Bengal-sensitized photo-oxidation of 1-methyl-3-indoleacetic acid in aqueous buffer (pH 5 or pH 8) containing 10% methanol has been studied.