Chemical Properties
copper or brown-red crystalline powder
Uses
Acridine Yellow G may be useful in the preparations of aptamers for targeting coagulation factor XIII for treatment of thrombosis.
Biochem/physiol Actions
Acridine Yellow G (AYG) is an organic dye with photophysical properties. It is widely used in optics, medicine and photovoltaic cells. AYG has been used as a solar photocatalyst to increase biodegradability and remove ferulic acid, a target pollutant from wastewater. It retards the growth of glioblastoma via dual inhibition of epidermal growth factor receptor and protein kinase c kinases.
Purification Methods
Note that the hydrochloride is normally called Acridine Yellow G and not the free base. The free base recrystallises from 1:1 *benzene/methanol, or from 800 parts of EtOH. It is converted to the sparingly soluble hydrochloride with dilute HCl, filtered off and dried. [Albert J Chem Soc 248 1947, Beilstein 22 III/IV 5499, 22/11 V 340.]
