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ERYTHROSIN B Structure

ERYTHROSIN B

Chemical Properties

Melting point 303 °C (dec.)(lit.)
Boiling point 628.3±55.0 °C(Predicted)
Density  2.4391 (estimate)
storage temp.  room temp
solubility  spirit: soluble
form  powder
pka 7.21±0.20(Predicted)
Colour Index  45430:2
color  Red
Water Solubility  Soluble in water, spirit, methanol, methyl cellosolve and ethanol.
EWG's Food Scores 1
FDA UNII 1A878FZQ9B
EPA Substance Registry System 2',4',5',7'-Tetraiodofluorescein (15905-32-5)

Safety

Symbol(GHS) GHS hazard pictograms
Signal wordDanger
Hazard statements H314-H290
Precautionary statements P501-P234-P264-P280-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P406-P405
Safety Statements  22-24/25
WGK Germany  2
RTECS  LM5940000
TSCA  Yes
HS Code  29329990
Toxicity A food color formerly approved for use in the United States and Europe. It was used primarily in jams and marmalades, maraschino cherries, pickles and relishes, etc. The LD50 in rats is 150 mg/kg, i.p., and 600 mg/kg, p.o. Erythrosine has a variety of actions in vitro due in large measure to its ability to affect biological membranes and lipophilic sites of enzymes. Such data have led to the hypothesis that erythrosine could be neurotoxic, but both clinical and preclinical data have suggested that erythrosine is not likely to be neurotoxic at doses that might be encountered. Two other toxicological issues have been raised with this food color. It has been suggested to be a potential, if weak, carcinogen, and it may also contribute to potential thyroid toxicity resulting from release of iodine.
NFPA 704:
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