15905-32-5

Name ERYTHROSIN B
CAS 15905-32-5
EINECS(EC#) 240-046-0
Molecular Formula C20H8I4O5
MDL Number MFCD00005044
Molecular Weight 835.89
MOL File 15905-32-5.mol
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Chemical Properties

Appearance orange-red fine powder
Melting point  303 °C (dec.)(lit.)
Boiling point  628.3±55.0 °C(Predicted)
density  2.4391 (estimate)
storage temp.  Store at RT.
solubility  spirit: soluble
Colour Index  45430:2
form  powder
pka 7.21±0.20(Predicted)
color  Red
Water Solubility  Soluble in water, spirit, methanol, methyl cellosolve and ethanol.
ε(extinction coefficient) ≥102000 at 526-534nm at 0.005g/L (95% Methanol 5% 0.1M Na2CO3)
≥13000 at 310-318nm in 1 M NH4OH at 0.005g/L (95% Methanol 5% 0.1M Na2CO3)
≥32000 at 258-266nm at 0.005g/L (95% Methanol 5% 0.1M Na2CO3)
Major Application diagnostic assay manufacturing
hematology
histology
InChI 1S/C20H8I4O5/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20/h1-6,25-26H
InChIKey OALHHIHQOFIMEF-UHFFFAOYSA-N
SMILES Oc1c(I)cc2c(Oc3c(I)c(O)c(I)cc3C24OC(=O)c5ccccc45)c1I
Uses
Indicator in analytical chemistry.
EPA Substance Registry System 2',4',5',7'-Tetraiodofluorescein (15905-32-5)

Safety Data

Safety Statements 
WGK Germany  2
RTECS  LM5940000
TSCA  Yes
HS Code  29329990
Storage Class 11 - Combustible Solids
Toxicity
A food color formerly approved for use in the United States and Europe. It was used primarily in jams and marmalades, maraschino cherries, pickles and relishes, etc. The LD50 in rats is 150 mg/kg, i.p., and 600 mg/kg, p.o. Erythrosine has a variety of actions in vitro due in large measure to its ability to affect biological membranes and lipophilic sites of enzymes. Such data have led to the hypothesis that erythrosine could be neurotoxic, but both clinical and preclinical data have suggested that erythrosine is not likely to be neurotoxic at doses that might be encountered. Two other toxicological issues have been raised with this food color. It has been suggested to be a potential, if weak, carcinogen, and it may also contribute to potential thyroid toxicity resulting from release of iodine.

Hazard Information

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