Allyltriphenylphosphonium bromide

Chemical Properties

white crystalline powder

Uses

Allyltriphenylphosphonium bromide is used for the first time in the preparation of DES. It has been shown to be part of Phosphonium salts, having antiviral activity against influenza virus A. It can be used in witting olefination of aldehydes for preparation of conjugated dienes.

Preparation

Allyltriphenylphosphonium bromide was synthesized from the reaction of triphenylphosphine and allyl bromide in dry toluene.

Application

Reactant for:
Preparation of a diol and carbamate chemistry library for common functional groups
Regioselective synthesis of alkenes via semihydrogenation and semihydrogenation-oxidation of dienes
Alkene addition of frustrated Lewis pairs
Olefination of N-sulfonyl imines for stereoselective synthesis of vinyl arenes
Wittig olefination of aldehydes for preparation of conjugated dienes
Tandem Michael addition / ylide olefination reactions for the synthesis of highly functionalized cyclohexadienes
Reaction of allyltriphenylphosphonium bromide and Garner's aldehyde in basic media provided β- hydroxy-1,3-dienes.
Methyl 3-(buta-1,3-dienyl)benzoate
1-(Buta-1,3-dienyl)-4-(trifluoromethyl)benzene
1-(Buta-1,3-dienyl)-2-chlorobenzene
1-Bromo-4-(buta-1,3-dienyl)benzene
Buta-1,3-dienylbenzene