1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE

Chemical Properties

White Solid

Uses

A metabolite of Carbamazepine (C175840).Representative lots contained 1-2% carbamazepine by HPLC.

Uses

A metabolite of Carbamazepine (C175840). Representative lots contained 1-2% carbamazepine by HPLC.

Uses

A metabolite of Carbamazepine. Representative lots contained 1-2% carbamazepine by HPLC

Definition

ChEBI: An epoxide and metabolite of carbamazepine.

General Description

Carbamazepine-10,11-epoxide is the primary, active metabolite in both urine and serum of carbamazepine, an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder as well as trigeminal neuralgia. Potential toxicity of the epoxide metabolite requires regular therapeutic drug monitoring by LC or LC/MS for patients taking carbamazepine.

Biochem/physiol Actions

First metabolite of carbamazepine