5-NITROOXINDOLE

Uses

• Reactant for synthesis of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors
• Reactant for preparation of Aurora kinase inhibitors
• Reactant for synthesis of 3-substituted 2-indolinone RET inhibitors
• Reactant for synthesis of 4-azachromeno[2,3-b]indol-11(6H)-ones and derivatives as analogs of ellipticine
• Reactant for preparation of [18F]fluorobenzylidene-indolinone as possible tyrosine kinase inhibitor for PET tumor imaging
• Reactant for preparation of 3-substituted indolin-2-ones as neuroprotective and toxic agents