Chemical Properties
white to slightly yellow powder
Uses
Employed in a facile sequencing technique for pseudouridylate residues in RNA.
Synthesis Reference(s)
1. Sheehan, J. C.; Hlavka, J. J. JOC 1956, 21, 439.
Synthesis
1-Cyclohexyl-3-(2- morpholinoethyl)carbodiimide Metho-p-toluenesulfonate is synthesized by quaternization of the corresponding carbodiimide with methyl p-toluenesulfonate. The carbodiimide is obtained by dehydration of the thiourea.
1
Precautions
1-Cyclohexyl-3-(2- morpholinoethyl)carbodiimide Metho-p-toluenesulfonate is assumed to be harmful by ingestion and skin contact.