Chemical Properties
SODIUM TETRADECYL SULFATE is white solid
Uses
Foaming, wetting, and emulsifying in cosmetic,
household, and industrial uses.
Uses
Sodium 1-tetradecyl sulfate is used as an anionic surfactant in nickel plating bath, pickling, electrolytic cleaning, welding, leather dyeing and rubles polishes. It is used to study the time course of liquid drainage and foam coarsening and to investigate the effects of sclerosant foam preparation. It is used for the treatment of varicose and spider veins of the leg.
brand name
Sotradecol (Bioniche); Sotradecol (Elkins-Sinn).
General Description
Tetradecyl sulfate sodium salt is a detergent-like sclerosant.
Clinical Use
Sodium tetradecyl sulfate has shown efficacy in treating varicose veins, telangiectasias, hemangioma, pyogenic granuloma, cherry angioma, Kaposi sarcoma, lymphangioma circumscriptum, digital mucous cyst, ganglion cyst, glomangioma, angiokeratoma of Fordyce, pseudocyst of the auricle, and verruca[1].
Side effects
Commonly reported side effects include pain, erythema, swelling, hyperpigmentation, telangiectatic matting, and ulceration. Serious side effects such as anaphylaxis, pulmonary embolism, stroke, and myocardial infarction have also been reported.
Safety Profile
Poison by intraperitoneal and intravenous routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and Na2O. See also SULFATES
Purification Methods
It recrystallises from absolute EtOH [Abu Hamdiyyah & Rahman J Phys Chem 91 1531 1987]. Itis hygroscopic.[Beilstein 1 H 716.]
References
[1] Helena A Jenkinson, Sirunya Silapunt, Kelly M Wilmas. “Sodium Tetradecyl Sulfate: A Review of Clinical Uses.” Dermatologic Surgery 43 11 (2017): 1313–1320.
