Description
Mulberroside A is isolated from the ethanol extract of Morus alba root. It has anti-tyrosinase and antioxidant activity and is widely used as an active ingredient in cosmetics.
Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Morus alba bark.
Uses
Mulberroside A is a stilbenoid found in Morus alba plants. Potential metabolite for Oxyresveratrol (O861920), a natural hydroxystilbene with similar bioactivity to resveratrol. COX-1 inhibitor like resveratrol (R150000), anti-cancer agent.
Definition
ChEBI: Cis-Mulberroside A is a glycoside and a stilbenoid.
in vivo
Mulberroside A (10, 20, and 40 mg/kg) decreases serum uric acid levels and increases urinary urate excretion and fractional excretion of uric acid in hyperuricemic micem[4].
| Animal Model: | Male Kun-Ming mice (20±2 g)[4] |
| Dosage: | 5, 10, 20, and 40 mg/kg; the dose volume 10 mL/kg body weight |
| Administration: | Orally initiated at 9:00 a.m. |
| Result: | 10, 20, and 40 mg/kg significantly increased urinary urate excretion in 24 h, resulting in a remarkable elevation of fractional excretion of uric acid (FEUA), and the highest dose completely reversed FEUA alteration of hyperuricemic mice to normal. |
