Halquinol

Originator

Capitrol,Westwood Squibb

Uses

Antiinfective, topical.

Uses

Halquinol is an antimicrobial compound belonging to the group of hydroxyl-quinolines indicated for use in poultry and swine. It depresses the activity of the gastro-intestinal tract, causing longer transit time of feed through the intestine, thereby enhancing digestion and absorption of nutrients. It increases weight gain and improve feed conversionprevent and control nonspecific diarrhea or wet dropping in farming animals.

Manufacturing Process

8-Quinolinol (mixture of 57-74% 5,7-dichloro-8-hydroxyquinoline, 23-40% 5- chloro-8-hydroxyquinoline and less than 3% 7-chloro-8-hydroxyquinoline) was synthesized by interaction of 8-hydroxyquinoline with sulfuryl chloride in glacial acetic acid at 50°C for 1.5 hours. The reaction mixture was cooled, pH was made 6.0 (by addition NH4OH). The suspension obtained was centrifuged, washed with water and the mixture of chlorohydroxyquinolines was dried.

brand name

Quinolor (Bristol-Myers Squibb).

Therapeutic Function

Antibacterial, Antidiarrheal, Antiseborreic