Application
Tris(tetrabutylammonium) hydrogen pyrophosphate was used for:
Reagent for pyrophosphorylation
reaction of isoprenoid derivatives
Pyrophosphorylation of nucleosides
Triphosphorylation of nucleosides
General Description
Tris(tetrabutylammonium) hydrogen pyrophosphate is a triphosphate that is used as a nucleophile in organic synthesis. It reacts with isopropyl alcohol to form the corresponding cyclic adducts, which can be isolated as the corresponding acetonitrile salts. Tris(tetrabutylammonium) hydrogen pyrophosphate is also used as an intermediate for the synthesis of other molecules, such as geranyl, and provides a predictable means of synthesizing isotopomers of these molecules. This molecule may be prepared by reacting ammonium bicarbonate with chloride and then adding isopropyl alcohol to the mixture.