Chemical Properties
white powder
Uses
For the in situ preparation of chiral hydrogenation catalysts.
General Description
(-)-2,3-
O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane is a
C2 chelating diphosphine ligand for transition metal complexes during asymmetric catalysis.
Purification Methods
It has been recrystallised from *C6H6/pet ether. After 2 recrystallisations from EtOH, it was pure by TLC on silica gel using Me2CO/hexane as solvent. [Kagan & Dang J Am Chem Soc 94 6429 1972.] Lanthanide shift reagents See in “Aliphatic Compounds”, Chapter 4, europium (III) acetate above and Eu(tmc)3 and Eu(tfc)3 below.
