Uses
Inecalcitol is a derivative of Vitamin D (V676045), the vitamin that mediates intestinal calcium absorbtion, bone calcium metabolism and probably, muscle activity. It occurs in and is isolated from fish liver oils.
References
[1] GUY EELEN. Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction.[J]. Molecular Pharmacology, 2005, 67 5: 1566-1573. DOI:
10.1124/mol.104.008730[2] L VERLINDEN. Two novel 14-Epi-analogues of 1,25-dihydroxyvitamin D3 inhibit the growth of human breast cancer cells in vitro and in vivo.[J]. Cancer research, 2000, 60 10: 2673-2679.
[3] PETRA DE HAES . 1,25-Dihydroxyvitamin D3 and analogues protect primary human keratinocytes against UVB-induced DNA damage[J]. Journal of photochemistry and photobiology. B, Biology, 2005, 78 2: Pages 141-148. DOI:
10.1016/j.jphotobiol.2004.09.010[4] MICHAEL S K WONG. Vitamin D derivatives acutely reduce endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat.[J]. American journal of physiology. Heart and circulatory physiology, 2008, 295 1: H289-96. DOI:
10.1152/ajpheart.00116.2008
