Description
Dibenzoyl-L-tartaric acid is a kind of white crystalline powder, and odorless, mildly bitter flavor, be slightly soluble in water, and pH value is 3-4, in acid, dissolves in ethanol and acetone and other organic solvent. Be widely used in chiral separation of racemic amine compounds. Because it is cheap, has stable properties, and is easy to recycle, it has good industrial application value.
Chemical Properties
Dibenzoyl-L-tartaric acid is white to light yellow crystal powde
Uses
(-)-Dibenzoyl-L-tartaric acid, anhydrous is used as a reagent used to produce chiral salts. Also used as organic chemical synthesis intermediate.
Application
Dibenzoyl-L-tartaric acid plays a crucial role in the resolution of chiral compounds, particularly in the separation of enantiomers of racemic mixtures.
Flammability and Explosibility
Not classified
Safety Profile
Dibenzoyl-L-tartaric acid is an eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Synthesis
A synthetic method of Dibenzoyl-L-tartaric acid includes the following steps: with L-tartaric acid and benzoyl chloride as raw materials, copper sulfate as a catalyst and toluene as a solvent, carrying out reaction to prepare L-dibenzoyl tartaric anhydride, carrying out hydrolysis with an equal amount of water and toluene to obtain the L-dibenzoyl tartaric acid, wherein the toluene serving as the solvent, as well as the water and the toluene in the hydrolysis step, can be repeatedly utilized.
References
[1] Patent: CN104496806, 2016, B. Location in patent: Paragraph 0099-0102
[2] Journal of Chemical Research, Miniprint, 1984, # 5, p. 1518 - 1530
