Chemical Properties
White to off white crystalline powder
Uses
Di-Me L-lysine derivative. The methylation of lysine in histone tails is a common posttranslational modification that functions in histone-regulated chromatin condensation, with binding of methylated lysine occurring in aromatic pockets on chromodomain proteins.
Definition
ChEBI: Fmoc-lys(ME)2-OH hcl is a member of fluorenes.
General Description
A novel derivative for the introduction of dimethyl-lysine during Fmoc SPPS. Ref [1] contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues.
The product number for this product was previously 04-12-1269.
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reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
