Uses
tert-Butylphenyl Diphenyl Phosphate is used in the construction of electrochemical sensor for heparin.
General Description
Clear colorless liquid.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
tert-Butylphenyl diphenyl phosphate hydrolyzes under acidic or basic conditions, and can react with oxidizing materials.
Health Hazard
ACUTE/CHRONIC HAZARDS: tert-Butylphenyl diphenyl phosphate emits toxic fumes when heated to decomposition.
Fire Hazard
tert-Butylphenyl diphenyl phosphate is combustible.
Synthesis
1. p-tert-Butylphenol reacts with phosphorus oxychloride catalyzed by anhydrous AlCl to form an intermediate.
2. This intermediate reacts with phenol. The temperature is raised and held under vacuum to remove by-products.
3. The reaction mixture is diluted with toluene/cyclohexane, washed with alkali and water, and concentrated to obtain the product.
