Description
A pyrrolizidine alkaloid isolated from Senecio rosmarinifolium Linn., the base
crystallizes as glistening laminae from either EtOH or Me2CO. It has [α]
24D -
91.5° (MeOH) or - 94° (EtOH) and yields a crystalline nitrate, m.p. 218°C
(dec.); [α]
20D - 91.5° (H20) and a methiodide, m.p. 251°C. On alkaline hydrolysis it furnishes rosmarinecine, CsH1S0 3N, m.p. 171-2°C; [α]
25D - 118.5°
(MeOH) and senecic acid, ClOH160 S, m.p. 151°C; [α]
25D + 11.8° (EtOH).
References
Richardson, Warren., J. Chem. Soc., 452 (1943)
Kropman, Warren., ibid, 700 (1950)
