Description
N-Succinimidyl 4-Azido-2,3,5,6—tetrafluorobenzoate (ATFB SE, ATFB-OSu) is a photo-activatable linker used as a versatile labeling agent for investigating biological receptors and for direct coating the surfaces of carbon and organic-based polymers. Upon exposure to light (max. absorption at 258nm), ATFB produces stabilized nitrene intermediates that readily undergo insertion and addition reactions with nearby molecules in moderate to good yields.
This compound is an activated N-hydroxysuccinimide ester (NHS ester, SE) derivative that can react to almost any primary or secondary amine group of biomolecules, such as proteins and peptides, as well as to small-molecule amines.
