Description
Etoxazole is an organofluorine acaricide. It induces toxicity in two-spotted spider mite (
T. urticae) larvae (LC
50 = 0.036 mg/L for the London reference strain) through inhibition of chitin synthase 1. It reduces acetylcholinesterase (AChE) activity in the freshwater fish
O. niloticus in a concentration-dependent manner. Etoxazole (2.2-22 mg/kg per day) inhibits the activity of catalase, glutathione peroxidase (GPX), and AChE in the liver and kidneys of rats in a dose-dependent manner. Formulations containing etoxazole have been used for the control of mites in agriculture.
Chemical Properties
Pale-yellow liquid when pure or reddish-brown
liquid or semisolid as a technical product. Mild odor.
Uses
Isotope labelled Etoxazole is a acaricide/insecticide that works via chitin biosynthesis inhibition for the control of mites. Used as a standard for Pesticide detection. Useful in cannabis testing kits as a component of pesticide mixes (P698235).
Definition
ChEBI: Etoxazole is an organofluorine acaricide.
Potential Exposure
Aromatic hydrocarbon; Thiazole fungicide Etridiazole is a fungicide used in some countries as
a seed treatment on barley, beans, corn, cotton, peanuts,
peas, sorghum, soybeans, safflower, and wheat. It is
also used on cotton for in-furrow application at planting, on
ornamental plants and shrubs by horticultural nurseries, on
nonbearing citrus and nonbearing coffee, and for golf
course fairways, tees and greens. Some states hold Special
Local Need registrations for use on tobacco transplants
Shipping
UN2810 Toxic liquids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required. Military driver shall be given full and
complete information regarding shipment and conditions in
case of emergency. AR 50-6 deals specifically with the
shipment of chemical agents. Shipments of agent will be
escorted in accordance with AR 740-32.
Incompatibilities
Diazo compounds can detonate. This
applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic
gases are formed by mixing materials of this class with
acids, aldehydes, amides, carbamates, cyanides, inorganic
fluorides, halogenated organics, isocyanates, ketones,
metals, nitrides, peroxides, phenols, epoxides, acyl halides,
and strong oxidizing or reducing agents. Flammable gases
are formed by mixing materials in this group with alkali
metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. This
chemical is sensitive to prolonged exposure to heat. This
chemical is incompatible with strong oxidizing agents
Waste Disposal
Incineration would be an
effective disposal procedure where permitted. If an efficient
incinerator is not available, the product should be mixed
with large amounts of combustible material and contact
with the smoke should be avoided. In accordance with
40CFR165, follow recommendations for the disposal of
pesticides and pesticide containers
