Description
Inosine-5''-monophosphate (IMP) is a substrate of IMP dehydrogenase (IMPDH), a NAD
+-dependent enzyme that generates xanthosine monophosphate. This is a rate-limiting step in the generation of guanosine monophosphate, which is important for DNA, RNA, and glycoprotein synthesis. Inhibitors of IMPDH, including ribavirin (Item No.
16757) and mycophenolate mofetil (Item No.
13988), have potential applications as antiviral and anti-cancer drugs. 5-Ribonucleosides, including IMP, are also involved in potentiating the umami taste sensation.
Uses
Inosine-5''-monophosphate Sodium Salt Hydrate can be used for synthesis of fresh sauce for casserole. It is a sodium salt hydrate form of Inosine 5''-monophosphate (I665003), which can be used in combination with an immune checkpoint inhibitor for cancer immunotherapy.
