Chemical Properties
colourless to yellow liquid
Uses
Bis(3-aminopropyl)amine (BAPA) can be used:
- To synthesize chitosan based hydrogels having potential biomedical applications.
- For the functionalization of nanoparticles to yield terminal ?NH2 groups for further modifications.
- As an internal dispersing agent for the synthesis of water-dispersible polyurethanes.
- As a ligand in the preparation of [Cu(bapa)]2[Mo(CN)8]·7H2O photomagnetic coordination polymer.
Uses
A structural homologue of the natural polyamine spermidine with antitumor activity that may make it useful as a antineoplastic agent.
Definition
ChEBI: Bis(3-aminopropyl)amine is a polyazaalkane. It has a role as an algal metabolite and a plant metabolite. It is a conjugate base of a bis(3-azaniumylpropyl)azanium.
General Description
A colorless liquid. Less dense than water. Flash point of 170°F. Very irritating to skin and eyes, and may be toxic by ingestion. Used to make soaps, dyes, and pharmaceuticals.
Air & Water Reactions
Water soluble.
Reactivity Profile
DIPROPYLENETRIAMINE neutralize acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. DIPROPYLENETRIAMINE can react with oxidizing materials .
Hazard
Toxic by ingestion and inhalation; irritant.
Health Hazard
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Safety Profile
Poison by skin contact. Moderately toxic by ingestion. A skin and severe eye irritant. When heated to decomposition it emits toxic fumes of NO,. An explosive
Purification Methods
Dry the amine with Na and distil it under vacuum. [Beilstein 4 IV 1278.]
