ChemicalBook CAS DataBase List 56-18-8

56-18-8

Name	DIPROPYLENETRIAMINE
CAS	56-18-8
EINECS(EC#)	200-261-2
Molecular Formula	C6H17N3
MDL Number	MFCD00008214
Molecular Weight	131.22
MOL File	56-18-8.mol

Synonyms

3,3'-DIAMINODIPROPYLAMINE 3,3-DIAMINODIPROPYLAMINE 3,3'-IMINOBISPROPYLAMINE 3,3-IMINOBISPROPYLAMINE 3,3'-IMINODIPROPYLAMINE BIS-(3-AMINOPROPYL)AMINE DIPROPYLENETRIAMINE IBPA IMINO BIS PROPYLAMINE IMINODIPROPYLAMINE N-(3-AMINOPROPYL)-1,3-PROPANEDIAMINE RARECHEM AL BW 0231 1,3-Propanediamine, N-(3-aminopropyl)- 1,7-Diamino-4-azaheptane 1-Propanamine, 3,3'-iminobis- 3,3’-diamino-dipropylamin 3,3’-iminobis-propylamin 3,3'-Iminopropylamine -3-Aminopropyl 3-Propanediamine,N-(3-aminopropyl)-1

Chemical Properties

Appearance	colourless to yellow liquid
Melting point	−14 °C(lit.)
Boiling point	151 °C50 mm Hg(lit.)
density	0.938 g/mL at 25 °C(lit.)
refractive index	n20/D 1.481(lit.)
Fp	245 °F
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
Water Solubility	Completely miscible in water
form	clear liquid
pka	pK1:8.02(＋2);pK2:9.70(＋1);pK3:10.70(0) (30°C)
color	Colorless to Almost colorless
Stability:	Air and light sensitive. Combustible. Incompatible with oxidizing agents.
BRN	1071254
Cosmetics Ingredients Functions	BUFFERING
InChI	1S/C6H17N3/c7-3-1-5-9-6-2-4-8/h9H,1-8H2
InChIKey	OTBHHUPVCYLGQO-UHFFFAOYSA-N
SMILES	NCCCNCCCN
LogP	-0.826 (est)
CAS DataBase Reference	56-18-8(CAS DataBase Reference)
EPA Substance Registry System	Norspermidine (56-18-8)

Safety Data

Symbol(GHS)	GHS05,GHS06,GHS08
Signal word	Danger
Hazard statements	H302-H311-H314-H317-H330-H341-H373
Precautionary statements	P201-P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338+P310
Hazard Codes	T+,C
Risk Statements	R22:Harmful if swallowed. R24:Toxic in contact with skin. R26:Very Toxic by inhalation. R35:Causes severe burns. R43:May cause sensitization by skin contact. less more
Safety Statements	S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . less more
RIDADR	UN 2269 8/PG 3
WGK Germany	2
RTECS	JL9450000
TSCA	TSCA listed
REACH Registrations	Active
HazardClass	8
PackingGroup	III
HS Code	29252900
Storage Class	6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
Hazard Classifications	Acute Tox. 1 Inhalation Acute Tox. 3 Dermal Acute Tox. 4 Oral Eye Dam. 1 Muta. 2 Skin Corr. 1A Skin Sens. 1A STOT RE 2
Safety Profile	Poison by skin contact. Moderately toxic by ingestion. A skin and severe eye irritant. When heated to decomposition it emits toxic fumes of NO,. An explosive less more

Hazard Information

General Description

A colorless liquid. Less dense than water. Flash point of 170°F. Very irritating to skin and eyes, and may be toxic by ingestion. Used to make soaps, dyes, and pharmaceuticals.

Reactivity Profile

3,3'-IMINODIPROPYLAMINE(56-18-8) neutralize acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. This compound can react with oxidizing materials .

Air & Water Reactions

Water soluble.

Hazard

Toxic by ingestion and inhalation; irritant.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

Chemical Properties

colourless to yellow liquid

Uses

Bis(3-aminopropyl)amine (BAPA) can be used:

To synthesize chitosan based hydrogels having potential biomedical applications.
For the functionalization of nanoparticles to yield terminal ?NH₂groups for further modifications.
As an internal dispersing agent for the synthesis of water-dispersible polyurethanes.
As a ligand in the preparation of [Cu(bapa)]₂[Mo(CN)₈]·7H₂O photomagnetic coordination polymer.

Uses

A structural homologue of the natural polyamine spermidine with antitumor activity that may make it useful as a antineoplastic agent.

Definition

ChEBI: Bis(3-aminopropyl)amine is a polyazaalkane. It has a role as an algal metabolite and a plant metabolite. It is a conjugate base of a bis(3-azaniumylpropyl)azanium.

Synthesis Reference(s)

The Journal of Organic Chemistry, 58, p. 3736, 1993 DOI: 10.1021/jo00066a028
Journal of the American Chemical Society, 105, p. 5002, 1983 DOI: 10.1021/ja00353a025

Purification Methods

Dry the amine with Na and distil it under vacuum. [Beilstein 4 IV 1278.]

Material Safety Data Sheet(MSDS)

Spectrum Detail

Well-known Reagent Company Product Information

Supplier

Hubei Paijian Biotechnology Co., Ltd

Telephone18164202469 18163347313

Website

Shanghai Nolai Giant Chemical Co. , Ltd.

Telephone 13012824065

Websitehttps://www.nuolaiju.com

Meryer (Shanghai) Chemical Technology Co., Ltd.

Telephone4006356688 18621169109

Websitehttp://www.x-labseek.com/

TCI (Shanghai) Development Co., Ltd.

Telephone021-67121386

Websitehttps://www.tcichemicals.com/CN/zh/

Energy Chemical

Telephone 400-0056266

Websitehttp://www.energy-chemical.com

Chemsky（shanghai）International Co.,Ltd.

Telephone021-50135380

Websitehttp://www.shchemsky.com

Shandong Xiya Chemical Co., Ltd

Telephone13355009207 13355009207

Websitehttp://www.xiyashiji.com

Tianjin heowns Biochemical Technology Co., Ltd.

Telephone400 638 7771

Websitehttp://www.heowns.com

Maya High Purity Chemicals

Telephone+86 (573) 82222445 (0)18006601000 452520369

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm

Thermo Fisher Scientific

Telephone800-810-5118

Websitehttp://www.thermo.com.cn

9ding chemical ( Shanghai) Limited

Telephone4009209199

Websitehttp://www.9dingchem.com

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Telephone+86-28-85122536 85324413

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList12313/0_EN.htm

Zouping Mingxing Chemical Co.,Ltd.

Telephone86-13605431940 13605431940

Websitehttp://www.zoutong.com.cn

Chengdu HuaXia Chemical Reagent Co. Ltd

Telephone400-1166-196 13458535857

Websitehttp://www.hx-r.com

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Telephone0510-85629785 18013409632;

Websitehttp://www.reading-chemicals.com

Shanghai Macklin Biochemical Co.,Ltd.

Telephone15221275939 15221275939

Websitehttp://www.macklin.cn

Sigma-Aldrich

Telephone021-61415566 800-8193336

Websitehttps://www.sigmaaldrich.cn

Jiangsu Qingquan Chemical Co., Ltd.

Telephone0571-86589382 57186589381

Websitehttp://www.qqpharm.com/

1of4

Related Products

Send Inquriy