Uses
Podocarpusflavone A is a DNA topoisomerase I inhibitor. Podocarpusflavone A has moderated anti-proliferative activity and induces cell apoptosis in MCF-7. Podocarpusflavone A is developing anti-tumor agents[1].
Definition
ChEBI: Podocarpusflavone a is a flavonoid oligomer.
IC 50
Topoisomerase I: 119.425 μM (IC
50)
References
[1] Pen-Ho Yeh et al. Naturally Occurring Cytotoxic [3′→8″]-Biflavonoids from Podocarpus nakaii
J Tradit Complement Med. 2012 Jul;2(3):220-6. DOI:
10.1016/s2225-4110(16)30103-1
