ascamycin

The Ascamycin has C2-chloroadenine as the base on C-1' which lacks the chlorine. Ascamycin has a selective antibacterial activity against Xanthomonas species. When Ascamycin is dealanylated, Dealanylascamycin shows a broad antibacterial activity against various Gram-negative and Gram-positive bacteria. Xanthomonas citri is susceptible to Ascamycin by virtue of the Ascamycin-dealanylating enzyme on the cell surface.

MIC: 0.4 μg/mL ( Xanthomonas citri ), 12.5 μg/mL ( Xanthomonas oryzae ) and 12.5 μg/mL ( Mycobacterium phlei )