DICHLOROBIS(METHYLDIPHENYLPHOSPHINE)PALLADIUM(II)

Uses

Catalyst for:

• Ullmann reactions (homocoupling reactions)
• Cross coupling reaction of tributyltin hydride with aryl iodides
• Double silylation, double carbonylation and cyclocarbonylation reactions

Application

Dichlorobis(methyldiphenylphosphine)palladium(II) is a catalyst for the dicarbonylation of aryl halides with amines.

Preparation

Dichlorobis(methyldiphenylphosphine)palladium(II) is prepared by treating commercially available K2PdCl2 (in DMF) with methyldiphenylphosphine (in CH2Cl2), or  from K2PdCl2 (in H2O) and methyldiphenylphosphine (in CH2Cl2) using Bu4NCl (in CH2Cl2) as a phase-transfer catalyst.

reaction suitability

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Cross Couplings
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst