1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Price

1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE Chemical Properties,Usage,Production

• Uses

  Activates apoptosis in cells; shows selectivity for cancer cells against normal cell lines

• Uses

  Apoptosis Activator 2 activates caspases in a cytochrome c-dependent manner and induces apoptosis in tumor cells.

• Biological Activity

  Apoptosis activator; promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC 50 = 4-9 μ M for leukaemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC 50 > 40 μ M).

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  1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE

  $5.00/ KG

  99%

  Career Henan Chemical Co

  Inquiry

79183-19-0, 1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONERelated Search