Uses
4-Nitrofluorobenzene, is an aryl fluorinated building block, and a common intermediate used for the synthesis of many industrial useful compounds. It is used for the preparation of novel soluble aromatic polyimides, such as 1,3,5-Tris(4-aminophenoxy)benzene (TAB).
Chemical Properties
yellow liquid
Uses
1-Fluoro-4-nitrobenzene used as a component of hair dyes, as pharmaceutical intermediates. It is also used for the preparation of novel soluble aromatic polyimides
Flammability and Explosibility
Non flammable
Synthesis
Synthesis of 4-fluoronitrobenzene. Reagents and conditions: (a) PCl5 (1.1 equiv.), PhPOCl2 (0.11 equiv.), 160°C, 8 h (<65%); (b) KF (1.5 equiv.), bis(phosphoranylidene)ammonium chloride (0.04 equiv.), DMSO, 150°C, 8 h (51%).
Purification Methods
Crystallise it from EtOH. [Beilstein 5 H 241, 5 IV 719.]
