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STERIGMATOCYSTIN

STERIGMATOCYSTIN Structure
STERIGMATOCYSTIN
  • CAS No.10048-13-2
  • Chemical Name:STERIGMATOCYSTIN
  • CBNumber:CB1475014
  • Molecular Formula:C18H12O6
  • Formula Weight:324.28
  • MOL File:10048-13-2.mol
STERIGMATOCYSTIN Property
  • Melting point: :249-251℃
  • Boiling point: :382.63°C (rough estimate)
  • Density  :1.2842 (rough estimate)
  • refractive index  :1.4800 (estimate)
  • Flash point: :6℃
  • storage temp.  :2-8°C
  • pka :6.92±0.20(Predicted)
  • form  :powder
  • color  :yellow
  • BRN  :53259
  • CAS DataBase Reference :10048-13-2
  • FDA UNII :5F95211S5Z
  • IARC :2B (Vol. 10, Sup 7) 1987
  • Proposition 65 List :Sterigmatocystin
  • EPA Substance Registry System :Sterigmatocystin (10048-13-2)
Safety
  • Hazard Codes  :T,Xn,F
  • Risk Statements  :25-40-36-20/21/22-11
  • Safety Statements  :36/37-45-16
  • RIDADR  :UN 3462 6.1/PG 3
  • WGK Germany  :3
  • RTECS  :LV1750000
  • F  :10
  • HazardClass  :6.1(b)
  • PackingGroup  :III
  • HS Code  :29329990
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H301-H351-H225-H302-H312-H319-H332
  • Precautionary statements P281-P301+P310-P210-P280-P305+P351+P338
STERIGMATOCYSTIN Price More Price(7)
  • Brand: Sigma-Aldrich
  • Product number: 32986
  • Product name : Sterigmatocystin solution
  • Purity: 50μg/mL in acetonitrile, analytical standard
  • Packaging: 1ml
  • Price: $328
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 32609
  • Product name : Sterigmatocystin
  • Purity: reference material
  • Packaging: 5mg
  • Price: $1020
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 11441
  • Product name : Sterigmatocystin
  • Purity: ≥98%
  • Packaging: 500μg
  • Price: $25
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 11441
  • Product name : Sterigmatocystin
  • Purity: ≥98%
  • Packaging: 1mg
  • Price: $40
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: S3255
  • Product name : Sterigmatocystin
  • Purity: powder, ≥98% (TLC)
  • Packaging: 1mg
  • Price: $65.2
  • Updated: 2021/03/22
  • Buy: Buy

STERIGMATOCYSTIN Chemical Properties,Usage,Production

  • Chemical Properties yellow needles or powder
  • Uses Sterigmatocystin is a carcinogenic mycotoxin that is struturally related to Aflatoxin. Sterigmatocystin has been shown to inhibit RNA synthesis in rat liver nuclei.
  • Uses Sterigmatocystin is a xanthone produced by several species of Aspergillus, isolated by a number of research groups in the 1950s as a mycotoxin associated with food and grain contamination. Sterigmatocystin is structurally related to the aflatoxins and, while it is considered to be mutagenic, teratogenic and carcinogenic, it is less widespread and potent than the aflatoxins. Sterigmatocystin, in the presence of microsomes, covalently binds to DNA. It uncouples oxidative phosphorylation but, unlike the aflatoxins, does not induce mitochondrial swelling or hinder Ca2+-induced swelling of mitochondria. Sterigmatocystin also inhibits acyl-CoA:cholesterol acyltransferase (ACAT) with selectivity for the ACAT2 isoenzyme.
  • Definition ChEBI: An organic heteropentacyclic compound whose skeleton comprises a xanthene ring system ortho-fused to a dihydrofuranofuran moiety. The parent of the class of sterigmatocystins.
  • Hazard Possible carcinogen; tumorigen; poison; mutagen; causes necrosis of the liver and kidney, and an inhibitory effect on orotic acid incorporation into nuclear RNA.
  • Safety Profile Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Poison by ingestion and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
  • Purification Methods It crystallises from amyl acetate, Me2CO or EtOH and sublimes in vacuo. It has UV max at 208, 235, 249 and 329nm (log  4.28, 4.39, 4.44 and 4.12). [UV: Bullock et al. J Chem Soc 4179, 1962, UV, IR: Holker & Mulheirn J Chem Soc, Chem Commun 1576, 1576 1968, Birkinshaw & Hammady Biochem J 65 162 1957.] This mycotoxin induces bone marrow changes in mice [Curry et al. Mutation Res 137 111 1984]. [Beilstein 19/10 V 575.]
STERIGMATOCYSTIN Preparation Products And Raw materials
Raw materials
Preparation Products
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10048-13-2, STERIGMATOCYSTINRelated Search:
  • SterigMatocystin froM Aspergillus Versicolor
  • NSC 201423 NSC 204985 Sterigmatocystin
  • (3aR,12cS)-3a,12c-Dihydro-8-hydroxy-6-Methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one
  • NSC 201423
  • NSC 204985
  • (3aR,12cS)-8-hydroxy-6-methoxy-3aH-furo[3',2':4,5]furo[2,3-c]xanthen-7(12cH)-one
  • STERIGMATOCYSTIN
  • STERIGMATOCYSTIN, ASPERGILLUS VERSICOLOR
  • STERIGMATOCYSTINE
  • Sterigmatocystin solution
  • ,(3ar-cis)-
  • 2’:4,5)furo(2,3-c)xanthen-7-one,3a,12c-dihydro-8-hydroxy-6-methoxy-7h-furo(3
  • 3a,12c-dihydro-8-hydroxy-6-methoxy-7h-furo(3’,2’:4,5)furo(2,3-c)xanthen-7-on
  • 3a,12c-dihydro-8-hydroxy-6-methoxy-7h-furo(3’,2’:4,5)furo(2,3-c)xanthen-7-one
  • 3a,12c-dihydro-8-hydroxy-6-methoxyfuro[3’,2’:4,5]furo[3,2-c]xanthen-7-one
  • 3A,12C-DIHYDRO-8-HYDROXY-6-METHOXY-7H-FUROL[3',2':4,5]FURO[2,3-C]XANTHEN-7-ONE
  • (3aR-cis)3a,12c-dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one
  • STERIGMATOCYSTIN VIAL WITH 5 MG*
  • (3aR)-3aβ,12cβ-Dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one
  • Sterigmatocystin,98%
  • Sterigmatocystin Solution (50μg/ml in Acetonitrile Solution)
  • 7H-Furo[3',2':4,5]furo[2,3-c]xanthen-7-one, 3a,12c-dihydro-8-hydroxy-6-methoxy-, (3aR,12cS)-
  • Sterigmatocystin-13C18 Solution, 25μg/mL
  • STERIGMATOCYSTIN USP/EP/BP
  • 10048-13-2
  • C18H12O6