Description
PEG13 is a polymer consisting of ethylene glycol subunits with two terminal hydroxyl groups. The hydroxyl groups can undergo reactions to further derivatize the compound. The hydrophilic properties of the PEG linker increases the water solubility properties of attached compounds in aqueous media.
Uses
Dodecaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Definition
ChEBI: Dodecaethylene glycol is a poly(ethylene glycol).
reaction suitability
reagent type: cross-linking reagent
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:
10.1016/j.ebiom.2018.09.005
