Uses
Prostaglandin F3α (PGF3α) is an eicosapentaenoic acid (EPA)-derived bioactive lipid mediator that has anti-cancer and anti-inflammatory effects. Prostaglandin F3α is a substrate of ABCC4 with a Km of 12.1 μM. Prostaglandin F3α can be used for the research of diabetes[1][2].
Definition
ChEBI: Prostaglandin F3alpha is a prostaglandin Falpha that is prosta-5,13,17-trien-1-oic acid carrying three hydroxy substituents at positions 9alpha, 11alpha and 15. It is a conjugate acid of a prostaglandin F3alpha(1-).
References
[1] Tanaka N, et al. Transport of eicosapentaenoic acid-derived PGE, PGF(3α), and TXB by ABCC4. PLoS One. 2014 Oct 2;9(10):e109270. DOI:
10.1371/journal.pone.0109270[2] Sailaja Devi MM, et al. Effect of prostaglandins against alloxan-induced diabetes mellitus. Prostaglandins Leukot Essent Fatty Acids. 2006 Jan;74(1):39-60. DOI:
10.1016/j.plefa.2005.09.003