Chemical Properties
Yellow to light brown powder
Uses
2-Methoxy-5-nitrophenol is used in the synthesis of potent VEGF and tyrosine kinase inhibitors. Also used in the synthesis of GABA analogues and phosphodiesterase inhibitors such as rolipram.
Definition
ChEBI: 2-Methoxy-5-nitrophenol is a member of 3-nitrophenols.
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 28, p. 1287, 1980
DOI: 10.1248/cpb.28.1287
General Description
2-Methoxy-5-nitrophenol is the substitution photoproduct formed on irradiation of 2-chloro-4-nitroanisole at 25°C in aqueous NaOH.
