Application
(±)-Mandelamide, also known as D,L-Mandelamide, is an amide compound that may be employed as an intermediate in pharmaceutical synthesis.
Definition
ChEBI: Mandelamide is a monocarboxylic acid amide that is phenylacetamide in which one of the benzylic hydrogens has been replaced by a hydroxy group. It is a monocarboxylic acid amide, a member of benzyl alcohols and a secondary alcohol. It is functionally related to a phenylacetic acid.
Synthesis
()-Mandelic acid amide can be prepared from benzaldehyde as the reaction raw material, reacted with hydrocyanic acid to prepare D,L-mandelic acid nitrile, and then hydrolyzed under acidic conditions to obtain D,L-mandelic acid amide.
