Chemical Properties
clear colorless to pale yellowish liquid
Chemical Properties
2-Ethyl-4-(2,2,3-trimethylcyclopent-3-en-yl)-but-2-en-1-ol is amixture of the (E)- and
(Z)-isomers. It is a pale yellow liquid with a powerful sandalwood odor and a slight
rose nuance. The mixture can be prepared starting from α-campholenaldehyde
and butanal. The intermediate unsaturated aldehyde is partially hydrogenated to
give the title alcohol.
It is used in perfume compositions for cosmetics, soaps, and detergents.
Uses
Sandacanol is a specific agonist of olfactory receptor (OR10H1). Sandacanol induces cell cycle arrest and some apoptosis in bladder cancer cells[1].
Trade name
Bacdanol® (IFF), Sandacanol (Hangzhou), Sanderol (DRT),
Sandranol® (Symrise), Sanjinol (IFF).
References
[1] Lea Weber, et al. Characterization of the Olfactory Receptor OR10H1 in Human Urinary Bladder Cancer. Front Physiol. 2018 May 16;9:456. DOI:
10.3389/fphys.2018.00456
