Chemical Properties
2-Phenyl-6-hydroxy-3-pyridazinone is white powdery crystal, m.p. 268~272℃, easily soluble in dimethylformamide and 1-methyl-2-pyrrolidone, insoluble in water, methanol, benzene, can form the corresponding salts with a variety of alkaline substances, stable in acidic, neutral and alkaline solutions, decomposed when encountering strong oxidizing agents.
Definition
ChEBI: 6-hydroxy-2-phenylpyridazin-3-one is a pyridazinone.
Synthesis
It was prepared by condensing phenylhydrazine with maleic anhydride to obtain 6-hydroxy-2-phenyl-3-pyridone. Dissolve phenylhydrazine hydrochloride in water, stirring and heating to 95 , once added maleic anhydride, reflux 2h, cooling precipitation of light yellow solid, filtration, water wash, filter cake with hot 10% sodium carbonate solution, filtration, water wash until the wash solution is free of chlorine ions, the filter cake after drying that is 6-hydroxy-2-phenyl-3-pyridone.
