macbecin I

macbecin I Structure
macbecin I
  • CAS No.73341-72-7
  • Chemical Name:macbecin I
  • CBNumber:CB11346962
  • Molecular Formula:C30H42N2O8
  • Formula Weight:558.66
  • MOL File:73341-72-7.mol
macbecin I Property
  • Melting point: :205-206 °C(Solv: ethanol (64-17-5); water (7732-18-5))
  • Boiling point: :736.2±60.0 °C(Predicted)
  • Density  :1.17±0.1 g/cm3(Predicted)
  • storage temp.  :Desiccate at -20°C
  • pka :8.62±0.70(Predicted)
  • EWG's Food Scores :1
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
macbecin I Price More Price(1)
  • Brand: Cayman Chemical
  • Product number: 22225
  • Product name : Macbecin I
  • Purity: ≥95%
  • Packaging: 1mg
  • Price: $239
  • Updated: 2020/06/24
  • Buy: Buy

macbecin I Chemical Properties,Usage,Production

  • Biological Activity Ansamycin antibiotic compound that inhibits Hsp90 activity (IC 50 = 2 μ M) by binding to the ATP-binding site. Exhibits antitumor and cytocidal activities (IC 50 ~ 0.4 μ M) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Displays higher affinity and potency than geldanamycin (9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9-carbamate ).
macbecin I Preparation Products And Raw materials
Raw materials
Preparation Products
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73341-72-7, macbecin IRelated Search:
  • macbecin I
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  • (15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methyl-geldanamycin
  • Geldanamycin, 6,17-didemethoxy-15-methoxy-6-methyl-11-O-methyl-, (15R)-
  • 73341-72-7