Synthesis
The general procedure for synthesizing 2-nitroterephthalic acid from terephthalic acid (PTA) is as follows: 1 wt. part of PTA is mixed with 8 wt. parts of concentrated sulfuric acid at a concentration of 82% at 5°C, and 1 wt. part of 66% concentrated nitric acid is slowly added. The reaction mixture was heated to 60°C and maintained for 1 hour. Upon completion of the reaction, it was cooled to room temperature and vacuum filtered. The filter cake was mixed well with deionized water and heated to 80°C for 10 hours of reaction. The vacuum filtration operation was repeated until the filtrate was recrystallized in ice water. After filtration, the filtrate was dried under vacuum at 60 °C for 2 h to obtain 2-nitro terephthalic acid (PTANitro compound) with 93% purity and 68.6% yield.
References
[1] RSC Advances, 2016, vol. 6, # 10, p. 8495 - 8502
[2] Patent: CN103664684, 2016, B. Location in patent: Paragraph 0038
[3] Monatshefte fuer Chemie, 1886, vol. 7, p. 140
[4] Chemische Berichte, 1877, vol. 10, p. 145
[5] Justus Liebigs Annalen der Chemie, 1862, vol. 121, p. 90
