Uses
Immepip is a H3 agonist. Immepip can reduce cortical histamine release. Immepip can be used for the research of neurological diseases[1].
Definition
ChEBI: Immepip is a member of piperidines.
in vivo
Immepip (i.p.; 5, 10 mg/kg) markedly reduces cortical histamine release, but only weakly promotes sleep in the rat[1].
| Animal Model: | Sprague-Dawley rats[1] |
| Dosage: | 5, 10 mg/kg |
| Administration: | Intraperitoneally |
| Result: | Significantly modulated brain histamine release and slight, albeit significant, decreased in sleep onset latency. |
References
[1] Yves Lamberty, et al. H3 agonist immepip markedly reduces cortical histamine release, but only weakly promotes sleep in the rat. Pharmacol Res. 2003 Aug;48(2):193-8. DOI:
10.1016/s1043-6618(03)00094-x
