151070-83-6

Name	4-(1H-IMIDAZOL-4-YLMETHYL)-PIPERIDINE
CAS	151070-83-6
Molecular Formula	C9H15N3
MDL Number	MFCD00921728
Molecular Weight	165.24
MOL File	151070-83-6.mol

Synonyms

Immepip 4-(1H-imidazol-5-ylmethyl)piperidine 4-(1H-IMIDAZOL-4-YLMETHYL)-PIPERIDINE Piperidine, 4-(1H-imidazol-5-ylmethyl)-

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Chemical Properties

Boiling point	377.4±22.0 °C(Predicted)
density	1.084±0.06 g/cm3(Predicted)
pka	14?+-.0.10(Predicted)

Hazard Information

Uses

Immepip is a H3 agonist. Immepip can reduce cortical histamine release. Immepip can be used for the research of neurological diseases[1].

Definition

ChEBI: Immepip is a member of piperidines.

in vivo

Immepip (i.p.; 5, 10 mg/kg) markedly reduces cortical histamine release, but only weakly promotes sleep in the rat^[1].

Animal Model:	Sprague-Dawley rats^[1]
Dosage:	5, 10 mg/kg
Administration:	Intraperitoneally
Result:	Significantly modulated brain histamine release and slight, albeit significant, decreased in sleep onset latency.

References

[1] Yves Lamberty, et al. H3 agonist immepip markedly reduces cortical histamine release, but only weakly promotes sleep in the rat. Pharmacol Res. 2003 Aug;48(2):193-8. DOI:10.1016/s1043-6618(03)00094-x

Supplier

Jiangsu yize medical technology co. LTD

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Jinan ponder chemical co. LTD

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Haiji Pharmaceutical Technology (Suzhou) Co., Ltd

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TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

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