Chemical Properties
white to light yellow crystal powder.
Uses
2-Aminobenzyl alcohol was used in the synthesis of ethyl 2-hydroxymethylcarbanilate.
Application
A double dehydrogenative coupling of 2-aminobenzyl alcohol with secondary aryl alcohols furnishes 2-arylquinolines in good to excellent yields under mild and sustainable conditions. The reaction is catalyzed by the molecularly defined phosphine-free nickel complex.
General Description
2-Aminobenzyl alcohol is oxidatively cyclised with an array of ketones in dioxane at 80°C in the presence of a ruthenium catalyst and KOH to give corresponding quinolines. It undergoes oxidation catalyzed by heterotrimetallic RuMnMn species on the hydrotalcite surface in the presence of O
2 to yield 2-aminobenzaldehyde.
storage
Keep Cold. Air Sensitive. Light Sensitive.
