L-GLUTAMIC-2,3,3,4,4-D5 ACID

Chemical Properties

White Solid

Uses

A non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. It is also a key molecule in cellular metabolism.

Uses

L-Glutamic Acid-d5 is an non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. It is also a key molecule in cellular metabolism.

Definition

ChEBI: L-glutamic acid-d5 is a L-glutamic acid and a deuterated compound.

Biochem/physiol Actions

Glutamic acid (or glutamate) functions as a neurotransmitter and also serves as a precursor to other neurotransmitters such as gamma-aminobutyric acid. Glutamic acid also plays a key role in many metabolic pathways that controls growth, reproduction, maintenance and immunity. It is converted to α-ketoglutarate, a key component of the TCA (tricarboxylic acid) cycle and a precursor for the biosynthesis of nucleic acids and certain amino acids. In cells, glutamine is converted to glutamate by the enzyme glutaminase. Appl- L-Glutamic acid-2,3,3,4,4-d5 has been used as an internal standard in metabolomics and lipidomics profiling.