Synthesis
(R)-(+)-2,2'-Diamino-1,1'-binaphthalene can be 1a , 2b, potassium carbonate, potassium iodide, dimethyl sulfoxide as a reaction solvent, then react with adding potassium hydroxide, and finally extract with ethyl acetate And get.
Physical properties
(R)-(+)-2,2'-Diamino-1,1'-binaphthalene is a off-white to brown powder.
Uses
(R)-(+)-1,1'-Bi(2-naphthylamine) derivatives have been used for asymmetric hydrogenations, cyclopropanations and formation of chiral lactones. It can be used for the synthesis of sterically hindered binaphthalene-based monophosphane ligands.
General Description
(
R)-(+)-1,1′-Binaphthyl-2,2′-diamine is an axially dissymmetric binaphthyl ligand mainly used in enantioselective catalysis.
References
[1] Patent: CN107814729, 2018, A. Location in patent: Paragraph 0170-0173; 0254-0257
[2] Organic and Biomolecular Chemistry, 2016, vol. 14, # 38, p. 9021 - 9032
