Description
Difethialone[104653-34-1], 3-[(1RS,3RS; 1RS,3SR)-3-
(4 -bromobiphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthyl]-
4-hydroxy-1-benzothiin-2-one, C31H23BrO2S, MW 539.5,
mp 233–236 ?C, is a slightly yellowish powder which
is practically insoluble in water, moderately soluble in
ethanol, methanol, hexane, acetone, readily soluble in chloroform,
dimethylformamide [9, p. 393].
Uses
Difethialone is an anticoagulant rodenticide widely used to control rodent infestations.
Definition
ChEBI: Difethialone is a member of benzenes, a member of naphthalenes and a ring assembly.
Preparation
Difethialone is made by condensation of 4-hydroxy-2H-
1-benzothiapyran-2-one with 3-(4 -bromo-4-biphenyl)-1,2,
3,4-tetrahydro-1-naphthol in acetic acid containing concentrated
sulfuric acid (62).
Agricultural Uses
Rodenticide, Pesticide: Introduced in 1986, this second-generation anticoagulant rodenticide (member of the hydroxy-4-benzothiopyranone family) is used to control mice and rats, including
those resistant to first-generation anticoagulants. Not approved for use in most EU countries. Approved for use
in the U.S.
Trade name
LM-2219®; PROTECTA RAT BAIT
STATION®; VETERAN PELLET®; VETERAN WAX
BLOCK®
